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XBI
SPDR S&P Biotech ETFETF · Themes
$160.46+$3.91 (+2.50%)as of market close, Jul 2, 2026
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XBI weekly returns

SPDR S&P Biotech ETF has averaged 0.30% per week, positive in 56% of weeks. Week-by-week returns for SPDR S&P Biotech ETF (XBI) below, through July 2, 2026 — the table lists the most recent weeks; the bar chart plots the last 2 years.

Average week
+0.3%
1064 weeks
Best week
+20.7%
Nov 11, 2016
Worst week
-16.5%
Oct 10, 2008
Positive weeks
56%
of all weeks

SPDR S&P Biotech ETF weekly returns#

SPDR S&P Biotech ETF total return by week
Week endingTotal return
Jul 2, 2026
+3.3%
Jun 26, 2026
+10.5%
Jun 18, 2026
+5.1%
Jun 12, 2026
+4.0%
Jun 5, 2026
-5.9%
May 29, 2026
+3.8%
May 22, 2026
+0.7%
May 15, 2026
-3.0%
May 8, 2026
+3.3%
May 1, 2026
-2.1%
Apr 24, 2026
-3.9%
Apr 17, 2026
+7.1%

Weekly total return (since Jul 12, 2024)

-10%-5%+0%+5%+10%
20252026

Methodology#

Weekly returns are total returns (dividends reinvested), computed from XBI's split- and dividend-adjusted weekly (ISO week) closes. The table shows the most recent 260 weeks and the bar chart the most recent 104. See the year-by-year returns for the annual view. Past performance does not predict future returns; not investment advice.

See also: S&P 500 · Nasdaq-100 · Dow Jones · Russell 2000 · US Bond Market · Gold · Silver · Bitcoin · Ethereum

FAQ

What is SPDR S&P Biotech ETF's average weekly return?
SPDR S&P Biotech ETF (XBI) has averaged about 0.30% per week, positive in roughly 56% of weeks. The best week was Nov 11, 2016 (+20.7%) and the worst was Oct 10, 2008 (-16.5%).