XBI — SPDR S&P Biotech ETF stock price and chart

XBI

$154.84+2.90%

as of close, Oct 27, 2026

☾ AH $154.84 +2.90%

SPDR S&P Biotech ETFETF · Themes

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Technical analysis2

Overlay lines0

Addendum charts0

VolumeDDDDDDDDDDDDDDDDDDDDDDDDD

20162019202120242026

60.070.080.090.0100.0110.0120.0130.0140.0150.0160.0050.0M100.0M$154.84

2026-10-27

Price$154.84

MA20$150.70

MA50$131.28

Vol31.7M

What would $1,000 invested in XBI be worth today? →

XBI returns: By year · By month · By week · Trailing

Fund facts#

Expense ratio: 0.35%
YTD total return: +27.12%
YTD price return: +26.99%
Avg return 3Y: +33.17%
Avg return 5Y: +4.38%
AUM: $10.7B (2026-06-30)
Issuer: State Street
52W low: $106.30
52W high: $169.89
Inception: 2006-01-31

Performance · price return · as of 2026-10-27#

+2.90%

+1.04%

-0.12%

+2.82%

YTD

+26.99%

+38.76%

+26.69%

About XBI#

“The State Street SPDR S&P Biotech ETF (the Fund) seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index.”

Tracks: S&P Biotechnology Select Industry IndexObjective as stated in the fund’s SEC prospectus filing.Official SEC filings ↗

Holdings#

151 holdings · top 10 = 19% · filed Jun 30, 2026

Top 10 holdings

CompanyWeight1D

1MRNAModerna Inc.

4.1%+4.6%

2TWSTTwist Bioscience Corporation

2.2%+10.1%

3GRALGRAIL Inc. Common Stock

2.0%+7.5%

4IOVAIovance Biotherapeutics Inc.

1.9%+5.8%

5NTRANatera Inc.

1.7%+1.4%

6HALOHalozyme Therapeutics Inc.

1.7%+0.4%

7Apogee Therapeutics Inc

1.5%—

8KYMRKymera Therapeutics Inc.

1.4%+2.3%

9ORKAOruka Therapeutics Inc.

1.4%+6.2%

10KODKodiak Sciences Inc

1.3%+2.0%

Sector weights

SectorWeight

Healthcare

85.6%

Not on ChartRow

13.8%

Financials

0.6%

Estimated portfolio characteristics

P/B

5.3

Dividend yield

0.10%

Earnings growth (TTM)

-91.4%

Estimated by our own bottom-up analysis of the fund’s SEC-filed holdings; recomputed daily from public data.

All 151 holdings with weights and returns →

Annualized returns (CAGR)#

XBI

+42.7%+26.4%+34.3%+4.5%+10.7%+13.9%+11.9%1Ysince 10/20/252Ysince 10/21/243Ysince 10/23/235Ysince 10/25/2110Ysince 10/24/1615Ysince 10/24/1120Ysince 10/23/06

+0%+10%+20%+30%+40%

Compound annual growth rate per holding period, total return (dividends reinvested), from weekly adjusted closes. Each column is anchored at the date under it; horizons the fund’s history can’t span are omitted.

Fund flows#

6M 3Y · quarterly Max · yearly

XBI

+$307.4M−$443.2M−$589.5M+$633.3M−$223.6M+$918.7MJan 2026Feb 2026Mar 2026Apr 2026May 2026Jun 2026

−$500M$0$500M

XBI

−$210.6M+$147.5M+$144M−$191.3M+$110.1M−$650.2M−$684.8M−$378.6M−$88.8M+$817M−$725.3M+$1.3BQ3 2023Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026

−$500M$0$500M$1B

XBI

−$417.2M+$498.3M+$1.7B+$2.7B−$1.6B−$587.5M−$335.2M+$603.1M2019 YTD2020202120222023202420252026

−$1B$0$1B$2B

Net creations minus redemptions per period, from the fund’s SEC Form N-PORT filings (series-level: where a fund shares its portfolio with mutual-fund share classes, flows cover all classes combined). Quarterly filings publish with a ~60-day lag, so recent months appear as filings land. Flow data begins mid-2019 — Form N-PORT did not exist before then, for any fund.

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XBI — SPDR S&P Biotech ETF price, chart and key statistics