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XBI
SPDR S&P Biotech ETFETF · Themes
$156.20-0.40%
as of market close, Sep 11, 2026
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XBI — SPDR S&P Biotech ETF price, chart and key statistics

Technical analysis2
Overlay lines0
Addendum charts0
What would $1,000 invested in XBI be worth today? →
XBI returns: By year · By month · By week · Trailing

Fund facts

Expense ratio
0.35%
Distribution yield
0.37%
YTD (total return)
+28.23%
YTD (price only)
+28.11%
Avg return 3Y
+25.71%
Avg return 5Y
+3.60%
AUM
$10.7B (2026-06-30)
Issuer
State Street
52W low
$92.64
52W high
$169.89
Inception
2006-01-31

Performance · price return · windows as of 2026-09-11

1D
-0.40%
5D
-4.98%
1M
-2.00%
3M
+17.79%
YTD
+28.23%
1Y
+67.11%
5Y
+15.13%

About XBI

“The State Street SPDR S&P Biotech ETF (the Fund) seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the biotechnology segment of a U.S. total market composite index.”

Tracks: S&P Biotechnology Select Industry IndexObjective as stated in the fund’s SEC prospectus filing.Official SEC filings ↗

Holdings

151 holdings · top 10 = 15% · filed Jun 30, 2026

Top 10 holdings

CompanyWeight
1MRNAModerna Inc.
2.8%
2APGEApogee Therapeutics Inc.
1.5%
3HALOHalozyme Therapeutics Inc.
1.4%
4NTRANatera Inc.
1.4%
5Twist Bioscience Corp
1.4%
6Oruka Therapeutics Inc
1.3%
7Kymera Therapeutics Inc
1.3%
8ROIVRoivant Sciences Ltd.
1.3%
9RVMDRevolution Medicines Inc.
1.3%
10INSMInsmed Incorporated
1.3%

Sector weights

SectorWeight
Not on ChartRow
70.8%
Healthcare
29.2%

Annualized returns (CAGR)

XBI

Compound annual growth rate per holding period, total return (dividends reinvested), from weekly adjusted closes. Each column is anchored at the date under it; horizons the fund’s history can’t span are omitted.

Fund flows

XBI
XBI
XBI

Net creations minus redemptions per period, from the fund’s SEC Form N-PORT filings (series-level: where a fund shares its portfolio with mutual-fund share classes, flows cover all classes combined). Quarterly filings publish with a ~60-day lag, so recent months appear as filings land. Flow data begins mid-2019 — Form N-PORT did not exist before then, for any fund.

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SPDR S&P Biotech ETF (XBI) is a Themes ETF that trades at $156.20. This page has a live price, an interactive chart with 20+ years of price history, total returns, distribution yield, expense ratio, and key metrics.