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XBI
$144.32-3.65%
as of close, Oct 16, 2026
☾ AH $144.32 -3.65%
SPDR S&P Biotech ETFETF · Themes
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SPDR S&P Biotech ETF trailing returns

SPDR S&P Biotech ETF's 10-year return is +9.4% a year (CAGR) (+145.7% cumulative). How SPDR S&P Biotech ETF (XBI) has performed over the last day, week, month and year, over 5, 10 and 20 years, and since inception, through October 16, 2026 — price return and dividends side by side, with the worst drop inside each window.

Trailing returns by period#

To 2026-10-16. Price return + dividends = total return. Per year (CAGR) for windows of a year or more, with the cumulative total return beneath. Worst drop: the deepest fall in the price from a high inside the window, and when it bottomed.

PeriodPriceDivsTotalWorst drop
1 day-3.6%+0.0%-3.6%—
5 days-6.1%+0.0%-6.1%-6.1%Oct 16
1 month-6.4%+0.0%-6.4%-10.8%Oct 16
YTD+18.4%+0.1%+18.5%-14.9%Oct 16
1 year+33.7%+0.6%+34.3%-14.9%Oct 2026
5 years+2.9%+0.1%+3.0%+16.1%-53.2%May 2022
10 years+9.3%+0.2%+9.4%+145.7%-63.9%May 2022
20 years+11.5%+0.2%+11.7%+811.3%-63.9%May 2022
Since inception (2006)+11.1%+0.2%+11.2%+807.2%-63.9%May 2022

Growth of XBI#

Actual level with dividends reinvested (solid); dashed lines are each window's constant-rate path from start to today.

  • 5 years+3.0%/year · +16.1%
  • 10 years+9.4%/year · +145.7%
  • 20 years+11.7%/year · +811.3%

Methodology#

Trailing returns measure from the closest close about N years before the latest close (2026-10-16). Cumulative return is the total change over the window; annualized return is the compound annual growth rate (CAGR), shown for windows of a year or more. Price return is the change in XBI's closing price; total return reinvests dividends (from its split- and dividend-adjusted closes); the dividends column is the difference between the two. The worst drop is the largest fall in the closing price from a high to a later low inside the window, the way a drawdown is usually quoted. See the year-by-year returns for the calendar breakdown. Past performance does not predict future returns; not investment advice.

FAQ#

What is SPDR S&P Biotech ETF's 10-year return?
Over the last 10 years, SPDR S&P Biotech ETF (XBI) returned about +9.4% a year annualized (+145.7% cumulative total return).
What is SPDR S&P Biotech ETF's 20-year annualized return?
Over the last 20 years, SPDR S&P Biotech ETF (XBI) compounded at about +11.7% a year (+811.3% cumulative).
What is SPDR S&P Biotech ETF's return since inception?
Since 2006, SPDR S&P Biotech ETF (XBI) has compounded at about +11.2% a year — +807.2% in total.

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