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XBI
SPDR S&P Biotech ETFETF · Themes
$160.11+$0.58 (+0.36%)as of market close, Aug 18, 2026
☾ After hours:$160.37+0.16%4:29 PM ET
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XBI trailing returns

SPDR S&P Biotech ETF's 10-year annualized return is +10.1% per year (+161.9% cumulative). How SPDR S&P Biotech ETF (XBI) has performed over the last day, week, month and year, over 5, 10 and 20 years, and since inception, through August 18, 2026 — cumulative and annualized, with dividends on or off.

Trailing returns by period#

To 2026-08-18. Annualized (CAGR) for windows of a year or more.

PeriodPathAnnualizedCumulative
1 day+0.4%
1 week+1.3%
1 month+6.1%
YTD+31.3%
1 year
+78.1%
+78.1%
5 years
+5.4%
+30.1%
10 years
+10.1%
+161.9%
20 years
+12.9%
+1027.3%
Since inception (2006)
+12.0%
+930.2%

Growth of XBI#

Actual index level (solid); dashed lines are each window's constant-rate path from start to today.

20.050.010020072010201320162019202220255 yearsAug 2021 → Aug 2026+30.1%+5.4%/year10 yearsAug 2016 → Aug 2026+161.9%+10.1%/year20 yearsAug 2006 → Aug 2026+1027.3%+12.9%/yearSince inception (2006)Feb 2006 → Aug 2026+930.2%+12.0%/year

Methodology#

Trailing returns measure from the closest close about N years before the latest close (2026-08-18). Cumulative return is the total change over the window; annualized return is the compound annual growth rate (CAGR), shown for windows of a year or more. Total return reinvests dividends (from XBI's split- and dividend-adjusted closes); price return excludes them. See the year-by-year returns for the calendar breakdown. Past performance does not predict future returns; not investment advice.

See also: S&P 500 · Nasdaq-100 · Dow Jones · Russell 2000 · US Bond Market · Gold · Silver · Bitcoin · Ethereum

FAQ#

What is SPDR S&P Biotech ETF's 10-year return?
Over the last 10 years, SPDR S&P Biotech ETF (XBI) returned about +10.1% a year annualized (+161.9% cumulative total return).
What is SPDR S&P Biotech ETF's 20-year annualized return?
Over the last 20 years, SPDR S&P Biotech ETF (XBI) compounded at about +12.9% a year (+1027.3% cumulative).
What is SPDR S&P Biotech ETF's return since inception?
Since 2006, SPDR S&P Biotech ETF (XBI) has compounded at about +12.0% a year — +930.2% in total.