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XBI
SPDR S&P Biotech ETFETF · Themes
$160.46+$3.91 (+2.50%)as of market close, Jul 2, 2026
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XBI trailing returns

SPDR S&P Biotech ETF's 10-year annualized return is +11.3% per year (+191.4% cumulative). How SPDR S&P Biotech ETF (XBI) has performed over the last day, week, month and year, over 5, 10 and 20 years, and since inception, through July 2, 2026 — cumulative and annualized, with dividends on or off.

Trailing returns by period#

To 2026-07-02. Annualized (CAGR) for windows of a year or more.

PeriodPathAnnualizedCumulative
1 day+2.5%
1 week+5.9%
1 month+25.6%
YTD+31.6%
1 year
+93.8%
+93.8%
5 years
+3.1%
+16.5%
10 years
+11.3%
+191.4%
20 years
+12.8%
+1008.1%
Since inception (2006)
+12.1%
+932.5%

Growth of XBI#

Actual index level (solid); dashed lines are each window's constant-rate path from start to today.

20.050.010020072010201320162019202220255 yearsJul 2021 → Jul 2026+16.5%+3.1%/year10 yearsJul 2016 → Jul 2026+191.4%+11.3%/year20 yearsJul 2006 → Jul 2026+1008.1%+12.8%/yearSince inception (2006)Feb 2006 → Jul 2026+932.5%+12.1%/year

Methodology#

Trailing returns measure from the closest close about N years before the latest close (2026-07-02). Cumulative return is the total change over the window; annualized return is the compound annual growth rate (CAGR), shown for windows of a year or more. Total return reinvests dividends (from XBI's split- and dividend-adjusted closes); price return excludes them. See the year-by-year returns for the calendar breakdown. Past performance does not predict future returns; not investment advice.

See also: S&P 500 · Nasdaq-100 · Dow Jones · Russell 2000 · US Bond Market · Gold · Silver · Bitcoin · Ethereum

FAQ

What is SPDR S&P Biotech ETF's 10-year return?
Over the last 10 years, SPDR S&P Biotech ETF (XBI) returned about +11.3% a year annualized (+191.4% cumulative total return).
What is SPDR S&P Biotech ETF's 20-year annualized return?
Over the last 20 years, SPDR S&P Biotech ETF (XBI) compounded at about +12.8% a year (+1008.1% cumulative).
What is SPDR S&P Biotech ETF's return since inception?
Since 2006, SPDR S&P Biotech ETF (XBI) has compounded at about +12.1% a year — +932.5% in total.