SYRE
$79.90-0.25%
Spyre Therapeutics Inc.Stock · HealthcareRussell 2000 0.2%Nasdaq Composite 0.02%US Stock Market 0.010%Russell 3000 0.009%
Spyre Therapeutics Inc. total returns by year (including dividends)
As of market close, Oct 16, 2026
Spyre Therapeutics Inc. total returns by year (2017–2026)#
Calendar-year returns with each year's path and its dividend contribution (dividend return = total minus price return). Every year has a direct link you can bookmark or share.
| Year | Start price | End price | Path | Dividend | Total return |
|---|---|---|---|---|---|
| 2026YTD | $32.76 | $79.90 | 0.0% | +143.9% | |
| 2025 | $23.28 | $32.76 | 0.0% | +40.7% | |
| 2024 | $21.52 | $23.28 | 0.0% | +8.2% | |
| 2023 | $11.25 | $21.52 | 0.0% | +91.3% | |
| 2022 | $118.75 | $11.25 | 0.0% | -90.5% | |
| 2021 | $196.75 | $118.75 | 0.0% | -39.6% | |
| 2020 | $191.00 | $196.75 | 0.0% | +3.0% | |
| 2019 | $187.25 | $191.00 | 0.0% | +2.0% | |
| 2018 | $135.25 | $187.25 | 0.0% | +38.4% | |
| 2017 | $108.75 | $135.25 | 0.0% | +24.4% |
- Annualized
- -9.2%
- 2017–2026
- Average year
- +8.6%
- 9 full years
- Best year
- +91.3%
- 2023
- Worst year
- -90.5%
- 2022
- Positive years
- 7/9
- 78% up
Annualized (CAGR)
-9.2%
2017–2026
Average year
+8.6%
9 full years
Best year
+91.3%
2023
Worst year
-90.5%
2022
Positive years
7/9
78% up
Total return by period#
Annual
-100%-50%0%50%100%
2017+24%'17
2018+38%'18
2019+2.0%'19
2020+3.0%'20
2021-40%'21
2022-91%'22
2023+91%'23
2024+8.2%'24
2025+41%'25
2026+144%'26
Methodology#
Total returns, dividends reinvested, measured on SYRE. Annualized return is the compound annual growth rate; the current year is year-to-date. Past performance does not predict future returns.
FAQ#
- What is Spyre Therapeutics Inc.'s average annual return?
- Since 2017, Spyre Therapeutics Inc. (SYRE) has returned about -9.2% a year (the compound annual growth rate) and an average calendar-year return of 8.6%.
- What were Spyre Therapeutics Inc.'s best and worst years?
- Over 2017–2026, the best year was 2023 (+91.3%) and the worst was 2022 (-90.5%).
- How often is Spyre Therapeutics Inc. up in a year?
- 7 of the 9 full years since 2017 were positive — about 78% of the time.
More on Spyre Therapeutics Inc.
Annual returns for: S&P 500 · S&P 500 Equal Weight · US Stock Market · Nasdaq-100