Spyre Therapeutics Inc. trailing returns
Spyre Therapeutics Inc.'s 10-year return is -7.2% a year (CAGR) (-52.7% cumulative). How Spyre Therapeutics Inc. (SYRE) has performed over the last day, week, month and year, over 5 and 10 years, and since inception, through October 16, 2026 — price return and dividends side by side, with the worst drop inside each window.
Trailing returns by period#
To 2026-10-16. Price return + dividends = total return. Per year (CAGR) for windows of a year or more, with the cumulative total return beneath. Worst drop: the deepest fall in the price from a high inside the window, and when it bottomed.
| Period | Price | DivsDividends | Total | Worst drop |
|---|---|---|---|---|
| 1 day | -0.2% | +0.0% | -0.2% | — |
| 5 days | -6.8% | +0.0% | -6.8% | -8.5%Oct 14 |
| 1 month | -12.4% | +0.0% | -12.4% | -15.6%Oct 14 |
| YTD | +143.9% | +0.0% | +143.9% | -27.8%Oct 14 |
| 1 year | +259.3% | +0.0% | +259.3% | -27.8%Oct 2026 |
| 5 years | -17.1% | +0.0% | -17.1%-60.9% | -98.7%Jun 2023 |
| 10 years | -7.2% | +0.0% | -7.2%-52.7% | -99.0%Jun 2023 |
| Since inception (2016) | -10.1% | +0.0% | -10.1%-67.3% | -99.1%Jun 2023 |
Growth of SYRE#
Actual level with dividends reinvested (solid); dashed lines are each window's constant-rate path from start to today.
- 5 years-17.1%/year · -60.9%
- 10 years-7.2%/year · -52.7%
Methodology#
Trailing returns measure from the closest close about N years before the latest close (2026-10-16). Cumulative return is the total change over the window; annualized return is the compound annual growth rate (CAGR), shown for windows of a year or more. Price return is the change in SYRE's closing price; total return reinvests dividends (from its split- and dividend-adjusted closes); the dividends column is the difference between the two. The worst drop is the largest fall in the closing price from a high to a later low inside the window, the way a drawdown is usually quoted. See the year-by-year returns for the calendar breakdown. Past performance does not predict future returns; not investment advice.
FAQ#
- What is Spyre Therapeutics Inc.'s 10-year return?
- Over the last 10 years, Spyre Therapeutics Inc. (SYRE) returned about -7.2% a year annualized (-52.7% cumulative total return).
- What is Spyre Therapeutics Inc.'s return since inception?
- Since 2016, Spyre Therapeutics Inc. (SYRE) has compounded at about -10.1% a year — -67.3% in total.