Septerna Inc. monthly returns
Septerna Inc. has averaged 5.92% per month, positive in 64% of months. Month-by-month returns for Septerna Inc. (SEPN) below, through October 20, 2026 — the table lists the most recent months; the bar chart plots the last 5 years.
Septerna Inc. monthly returns#
| Month | Path | Total return |
|---|---|---|
| Oct 2026 | +0.6% | |
| Sep 2026 | +2.6% | |
| Aug 2026 | +10.7% | |
| Jul 2026 | +2.9% | |
| Jun 2026 | +10.9% | |
| May 2026 | +27.1% | |
| Apr 2026 | -1.1% | |
| Mar 2026 | -17.2% | |
| Feb 2026 | +24.3% | |
| Jan 2026 | -16.3% | |
| Dec 2025 | -3.9% | |
| Nov 2025 | +40.9% | |
| Oct 2025 | +9.5% | |
| Sep 2025 | +55.5% | |
| Aug 2025 | -2.5% | |
| Jul 2025 | +17.4% | |
| Jun 2025 | +14.3% | |
| May 2025 | +32.9% | |
| Apr 2025 | +20.2% | |
| Mar 2025 | -10.5% | |
| Feb 2025 | -61.7% | |
| Jan 2025 | -26.2% | |
| Dec 2024 | -9.5% | |
| Nov 2024 | +10.5% |
Monthly total return (since Jan 2025)#
Septerna Inc. returns by calendar month#
Every month of every year since 2025, one tick per year on a shared scale; the dark bar is the month's average. Total returns, dividends reinvested.
October 2026 so far: +0.56% — 2nd of 2 Octobers since 2025 at the last close; the average October returned +9.5%.
| Month | −65%0+65% | Average | Median | Up | Best | Worst |
|---|---|---|---|---|---|---|
| Jan | -21.2% | -21.2% | 0% | -16.3% 2026 | -26.2% 2025 | |
| Feb | -18.7% | -18.7% | 50% | +24.3% 2026 | -61.7% 2025 | |
| Mar | -13.9% | -13.9% | 0% | -10.5% 2025 | -17.2% 2026 | |
| Apr | +9.5% | +9.5% | 50% | +20.2% 2025 | -1.1% 2026 | |
| May | +30.0% | +30.0% | 100% | +32.9% 2025 | +27.1% 2026 | |
| Jun | +12.6% | +12.6% | 100% | +14.3% 2025 | +10.9% 2026 | |
| Jul | +10.1% | +10.1% | 100% | +17.4% 2025 | +2.9% 2026 | |
| Aug | +4.1% | +4.1% | 50% | +10.7% 2026 | -2.5% 2025 | |
| Sep | +29.0% | +29.0% | 100% | +55.5% 2025 | +2.6% 2026 | |
| Oct | +9.5% | +9.5% | 100% | +9.5% 2025 | +9.5% 2025 | |
| Nov | +40.9% | +40.9% | 100% | +40.9% 2025 | +40.9% 2025 | |
| Dec | -3.9% | -3.9% | 0% | -3.9% 2025 | -3.9% 2025 |
Methodology#
Monthly returns are total returns (dividends reinvested), computed from SEPN's split- and dividend-adjusted month-end closes. The table shows the most recent 120 months and the bar chart the most recent 60. See the year-by-year returns for the annual view. Past performance does not predict future returns; not investment advice.
FAQ#
- What is Septerna Inc.'s average monthly return?
- Septerna Inc. (SEPN) has averaged about 5.92% per month, positive in roughly 64% of months. The best month was Sep 2025 (+55.5%) and the worst was Feb 2025 (-61.7%).