SEPN
$39.35+8.16%
Septerna Inc.Stock · HealthcareRussell 2000 · 0.02% of IWMNasdaq Composite · 0.005% of ONEQUS Stock Market · 0.001% of VTIRussell 3000 · 0.001% of IWV
Septerna Inc. total returns by year (including dividends)
As of market close, Oct 20, 2026
Septerna Inc. total returns by year (2025–2026)#
Calendar-year returns with each year's path and its dividend contribution (dividend return = total minus price return). Every year has a direct link you can bookmark or share.
| Year | Start price | End price | Path | Dividend | Total return |
|---|---|---|---|---|---|
| 2026YTD | $27.88 | $39.35 | 0.0% | +41.1% | |
| 2025 | $22.90 | $27.88 | 0.0% | +21.7% |
- Annualized
- +31.7%
- 2025–2026
- Average year
- +21.7%
- 1 full years
- Best year
- +21.7%
- 2025
- Worst year
- +21.7%
- 2025
- Positive years
- 1/1
- 100% up
Annualized (CAGR)
+31.7%
2025–2026
Average year
+21.7%
1 full years
Best year
+21.7%
2025
Worst year
+21.7%
2025
Positive years
1/1
100% up
Total return by period#
Annual
-40%-20%0%20%40%
2025+22%'25
2026+41%'26
Methodology#
Total returns, dividends reinvested, measured on SEPN. Annualized return is the compound annual growth rate; the current year is year-to-date. Past performance does not predict future returns.
FAQ#
- What is Septerna Inc.'s average annual return?
- Since 2025, Septerna Inc. (SEPN) has returned about 31.7% a year (the compound annual growth rate) and an average calendar-year return of 21.7%.
- What were Septerna Inc.'s best and worst years?
- Over 2025–2026, the best year was 2025 (+21.7%) and the worst was 2025 (+21.7%).
- How often is Septerna Inc. up in a year?
- 1 of the 1 full years since 2025 were positive — about 100% of the time.
More on Septerna Inc.
Annual returns for: S&P 500 · S&P 500 Equal Weight · US Stock Market · Nasdaq-100