IONS
$42.94-2.67%
Ionis Pharmaceuticals Inc.Stock · HealthcareNasdaq Composite 0.03%Russell 1000 0.02%Russell 3000 0.02%US Stock Market 0.02%
Ionis Pharmaceuticals Inc. total returns by year (including dividends)
As of market close, Oct 16, 2026
Ionis Pharmaceuticals Inc. total returns by year (1992–2026)#
Calendar-year returns with each year's path and its dividend contribution (dividend return = total minus price return). Every year has a direct link you can bookmark or share.
| Year | Start price | End price | Path | Dividend | Total return |
|---|---|---|---|---|---|
| 2026YTD | $79.11 | $42.94 | 0.0% | -45.7% | |
| 2025 | $34.96 | $79.11 | 0.0% | +126.3% | |
| 2024 | $50.59 | $34.96 | 0.0% | -30.9% | |
| 2023 | $37.77 | $50.59 | 0.0% | +33.9% | |
| 2022 | $30.43 | $37.77 | 0.0% | +24.1% | |
| 2021 | $56.54 | $30.43 | 0.0% | -46.2% | |
| 2020 | $60.41 | $56.54 | 0.0% | -6.4% | |
| 2019 | $54.06 | $60.41 | 0.0% | +11.7% | |
| 2018 | $50.30 | $54.06 | 0.0% | +7.5% | |
| 2017 | $47.83 | $50.30 | 0.0% | +5.2% | |
| 2016 | $61.93 | $47.83 | 0.0% | -22.8% | |
| 2015 | $61.74 | $61.93 | 0.0% | +0.3% | |
| 2014 | $39.84 | $61.74 | 0.0% | +55.0% | |
| 2013 | $10.44 | $39.84 | 0.0% | +281.6% | |
| 2012 | $7.21 | $10.44 | 0.0% | +44.8% | |
| 2011 | $10.12 | $7.21 | 0.0% | -28.8% | |
| 2010 | $11.11 | $10.12 | 0.0% | -8.9% | |
| 2009 | $14.18 | $11.11 | 0.0% | -21.7% | |
| 2008 | $15.75 | $14.18 | 0.0% | -10.0% | |
| 2007 | $11.12 | $15.75 | 0.0% | +41.6% | |
| 2006 | $5.24 | $11.12 | 0.0% | +112.2% | |
| 2005 | $5.90 | $5.24 | 0.0% | -11.2% | |
| 2004 | $6.50 | $5.90 | 0.0% | -9.2% | |
| 2003 | $6.59 | $6.50 | 0.0% | -1.4% | |
| 2002 | $22.19 | $6.59 | 0.0% | -70.3% | |
| 2001 | $10.63 | $22.19 | 0.0% | +108.8% | |
| 2000 | $6.25 | $10.63 | 0.0% | +70.0% | |
| 1999 | $12.94 | $6.25 | 0.0% | -51.7% | |
| 1998 | $12.31 | $12.94 | 0.0% | +5.1% | |
| 1997 | $18.00 | $12.31 | 0.0% | -31.6% | |
| 1996 | $13.13 | $18.00 | 0.0% | +37.1% | |
| 1995 | $4.00 | $13.13 | 0.0% | +228.1% | |
| 1994 | $6.75 | $4.00 | 0.0% | -40.7% | |
| 1993 | $9.75 | $6.75 | 0.0% | -30.8% | |
| 1992 | $13.75 | $9.75 | 0.0% | -29.1% |
- Annualized
- +4.4%
- 1992–2026
- Average year
- +21.8%
- 34 full years
- Best year
- +281.6%
- 2013
- Worst year
- -70.3%
- 2002
- Positive years
- 17/34
- 50% up
Annualized (CAGR)
+4.4%
1992–2026
Average year
+21.8%
34 full years
Best year
+281.6%
2013
Worst year
-70.3%
2002
Positive years
17/34
50% up
Total return by period#
Annual
-200%-100%0%100%200%
1992-29%'92
1993-31%
1994-41%
1995+228%'95
1996+37%
1997-32%
1998+5.1%'98
1999-52%
2000+70%
2001+109%'01
2002-70%
2003-1.4%
2004-9.2%'04
2005-11%
2006+112%
2007+42%'07
2008-10.0%
2009-22%
2010-8.9%'10
2011-29%
2012+45%
2013+282%'13
2014+55%
2015+0.31%
2016-23%'16
2017+5.2%
2018+7.5%
2019+12%'19
2020-6.4%
2021-46%
2022+24%'22
2023+34%
2024-31%
2025+126%'25
2026-46%
Methodology#
Total returns, dividends reinvested, measured on IONS. Annualized return is the compound annual growth rate; the current year is year-to-date. Past performance does not predict future returns.
FAQ#
- What is Ionis Pharmaceuticals Inc.'s average annual return?
- Since 1992, Ionis Pharmaceuticals Inc. (IONS) has returned about 4.4% a year (the compound annual growth rate) and an average calendar-year return of 21.8%.
- What were Ionis Pharmaceuticals Inc.'s best and worst years?
- Over 1992–2026, the best year was 2013 (+281.6%) and the worst was 2002 (-70.3%).
- How often is Ionis Pharmaceuticals Inc. up in a year?
- 17 of the 34 full years since 1992 were positive — about 50% of the time.
More on Ionis Pharmaceuticals Inc.
Annual returns for: S&P 500 · S&P 500 Equal Weight · US Stock Market · Nasdaq-100