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IONS
$42.94-2.67%
as of close, Oct 16, 2026
☾ AH $42.94 -2.67%
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Ionis Pharmaceuticals Inc. drawdown: 50.4% below the all-time high (price)

Ionis Pharmaceuticals Inc. is 50.4% below its all-time high, set Feb 6, 2026 (as of market close, Oct 16, 2026), measured on price alone — dividends are not included, the convention headlines and crash histories use. The chart shows every day as a percentage of the highest level reached up to that point: 100% means a fresh record, everything below is a drawdown.

Below all-time high
−50.4%
49.6% of ATH
All-time high
$86.5
Feb 6, 2026
Time below the high
8 mo
since Feb 6, 2026
Worst-ever drawdown
−91.7%
Mar 18, 2003
Longest underwater
13.5 yrs
between all-time highs
Today's level first reached
Jan 9, 2014
12.8 yrs ago
Last time this deep
Aug 29, 2025
in a previous episode

% of all-time high since 1991: price#

The classic underwater chart (drawdown curve), drawn as % of the all-time high — 100% is a fresh record, everything below it is time spent underwater. Basis and range are in the URL, so a particular view is a link.

Basis
Range
All-time high = 100%20%40%60%80%
IONS close · log5.0010.0020.0050.00
1995200020052010201520202025

The deepest drawdowns on record#

Every decline of 15% or more from an all-time high (price basis), deepest first.

PeakTroughDepthPeak → troughRecovered byUnderwater
Mar 6, 2000Mar 18, 2003−91.7%3.0 yrsSep 19, 201313.5 yrs
Nov 4, 1991Nov 4, 1994−84.1%3.0 yrsJun 10, 19964.6 yrs
Jun 10, 1996Dec 22, 1999−78.7%3.5 yrsMar 3, 20003.7 yrs
Mar 19, 2015Jun 27, 2016−73.2%15 moMar 14, 20194.0 yrs
Apr 8, 2019Apr 8, 2025−70.4%6.0 yrsFeb 6, 20266.8 yrs
Feb 21, 2014May 8, 2014−61.1%2 moDec 10, 201410 mo
Feb 6, 2026Oct 13, 2026−51.0%8 monot yet8 mo+
Sep 23, 2013Nov 18, 2013−20.9%56 daysNov 27, 20132 mo

Price basis (no dividends) — the convention crash histories use. With dividends reinvested, recoveries arrive years earlier; switch the basis on the chart above to see it.

Drawdown vs what came next#

One dot per month since 1991: how far Ionis Pharmaceuticals Inc. stood below its all-time high, and the total return over the following 1, 5 and 10 years.

1950–19992000–today

Read this with survivorship bias in mind: a single asset's history is one surviving sample, so past recoveries here say little about the odds ahead. Monthly windows also overlap heavily (they are not independent samples). Not investment advice.

FAQ#

How far is Ionis Pharmaceuticals Inc. from its all-time high?
Ionis Pharmaceuticals Inc. is currently 50.4% below its all-time high, set Feb 6, 2026 (as of market close, Oct 16, 2026). Prices only, the convention headlines use; with dividends reinvested the gap is usually smaller.
What was the biggest Ionis Pharmaceuticals Inc. drawdown ever?
The deepest decline on record in our data (since 1991) took Ionis Pharmaceuticals Inc. 91.7% below its prior high, bottoming Mar 18, 2003. The table on this page lists every major episode with its peak, trough and recovery date.

Methodology & related#

Daily data since -1 from IONS; no free deep history exists for Ionis Pharmaceuticals Inc. — for a 150-year drawdown record see the S&P 500 drawdown page. The price basis excludes dividends; the total-return basis reinvests them; the real basis additionally deflates by CPI. See also returns by year. Past performance does not predict future returns; not investment advice.

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