IONS
$42.94-2.67%
Ionis Pharmaceuticals Inc.Stock · HealthcareNasdaq Composite 0.03%Russell 1000 0.02%Russell 3000 0.02%US Stock Market 0.02%
Ionis Pharmaceuticals Inc. monthly returns
Ionis Pharmaceuticals Inc. has averaged 1.69% per month, positive in 49% of months. Month-by-month returns for Ionis Pharmaceuticals Inc. (IONS) below, through October 16, 2026 — the table lists the most recent months; the bar chart plots the last 5 years.
Average month
+1.7%
418 months
Best month
+91.7%
Nov 1992
Worst month
-60.0%
Dec 1999
Positive months
49%
of all months
Ionis Pharmaceuticals Inc. monthly returns#
| Month | Path | Total return |
|---|---|---|
| Oct 2026 | -3.8% | |
| Sep 2026 | -26.0% | |
| Aug 2026 | +16.6% | |
| Jul 2026 | -34.7% | |
| Jun 2026 | +3.6% | |
| May 2026 | +2.3% | |
| Apr 2026 | -0.4% | |
| Mar 2026 | -7.5% | |
| Feb 2026 | -1.8% | |
| Jan 2026 | +4.5% | |
| Dec 2025 | -4.4% | |
| Nov 2025 | +11.3% | |
| Oct 2025 | +13.6% | |
| Sep 2025 | +53.4% | |
| Aug 2025 | -0.8% | |
| Jul 2025 | +8.8% | |
| Jun 2025 | +17.9% | |
| May 2025 | +9.1% | |
| Apr 2025 | +1.8% | |
| Mar 2025 | -9.1% | |
| Feb 2025 | +4.0% | |
| Jan 2025 | -8.8% | |
| Dec 2024 | -2.2% | |
| Nov 2024 | -6.9% | |
| Oct 2024 | -4.2% | |
| Sep 2024 | -16.0% | |
| Aug 2024 | -3.6% | |
| Jul 2024 | +3.8% | |
| Jun 2024 | +26.9% | |
| May 2024 | -8.9% | |
| Apr 2024 | -4.8% | |
| Mar 2024 | -4.1% | |
| Feb 2024 | -12.0% | |
| Jan 2024 | +1.6% | |
| Dec 2023 | +2.3% | |
| Nov 2023 | +11.7% | |
| Oct 2023 | -2.4% | |
| Sep 2023 | +12.6% | |
| Aug 2023 | -2.8% | |
| Jul 2023 | +1.0% | |
| Jun 2023 | +0.3% | |
| May 2023 | +15.6% | |
| Apr 2023 | -1.0% | |
| Mar 2023 | -0.4% | |
| Feb 2023 | -10.0% | |
| Jan 2023 | +5.6% | |
| Dec 2022 | -7.4% | |
| Nov 2022 | -7.7% | |
| Oct 2022 | -0.1% | |
| Sep 2022 | +4.0% | |
| Aug 2022 | +13.2% | |
| Jul 2022 | +1.5% | |
| Jun 2022 | +1.4% | |
| May 2022 | -0.7% | |
| Apr 2022 | -0.8% | |
| Mar 2022 | +11.0% | |
| Feb 2022 | +5.0% | |
| Jan 2022 | +4.5% | |
| Dec 2021 | +14.8% | |
| Nov 2021 | -16.8% | |
| Oct 2021 | -5.0% | |
| Sep 2021 | -15.6% | |
| Aug 2021 | +7.1% | |
| Jul 2021 | -6.9% | |
| Jun 2021 | +7.1% | |
| May 2021 | -13.0% | |
| Apr 2021 | -4.8% | |
| Mar 2021 | -14.2% | |
| Feb 2021 | -12.8% | |
| Jan 2021 | +6.2% | |
| Dec 2020 | +11.9% | |
| Nov 2020 | +7.6% | |
| Oct 2020 | -1.1% | |
| Sep 2020 | -12.9% | |
| Aug 2020 | -5.3% | |
| Jul 2020 | -2.4% | |
| Jun 2020 | +4.9% | |
| May 2020 | +1.2% | |
| Apr 2020 | +17.4% | |
| Mar 2020 | -6.9% | |
| Feb 2020 | -12.9% | |
| Jan 2020 | -3.5% | |
| Dec 2019 | -5.6% | |
| Nov 2019 | +14.8% | |
| Oct 2019 | -7.0% | |
| Sep 2019 | -5.2% | |
| Aug 2019 | -4.0% | |
| Jul 2019 | +2.5% | |
| Jun 2019 | -2.0% | |
| May 2019 | -11.7% | |
| Apr 2019 | -8.4% | |
| Mar 2019 | +14.3% | |
| Feb 2019 | +22.4% | |
| Jan 2019 | +7.3% | |
| Dec 2018 | -7.3% | |
| Nov 2018 | +17.6% | |
| Oct 2018 | -3.9% | |
| Sep 2018 | +12.9% | |
| Aug 2018 | +4.6% | |
| Jul 2018 | +4.8% | |
| Jun 2018 | -10.7% | |
| May 2018 | +8.4% | |
| Apr 2018 | -2.4% | |
| Mar 2018 | -16.5% | |
| Feb 2018 | +0.6% | |
| Jan 2018 | +4.4% | |
| Dec 2017 | -9.4% | |
| Nov 2017 | -2.8% | |
| Oct 2017 | +12.6% | |
| Sep 2017 | -5.4% | |
| Aug 2017 | +2.3% | |
| Jul 2017 | +3.0% | |
| Jun 2017 | +11.1% | |
| May 2017 | -5.0% | |
| Apr 2017 | +19.9% | |
| Mar 2017 | -19.2% | |
| Feb 2017 | +11.8% | |
| Jan 2017 | -7.0% | |
| Dec 2016 | +9.3% | |
| Nov 2016 | +68.4% |
Monthly total return (since Nov 2021)#
-40%-20%0%20%40%
Nov 2021-17%
Dec 2021+15%
Jan 2022+4.5%2022
Feb 2022+5.0%
Mar 2022+11%
Apr 2022-0.76%
May 2022-0.65%
Jun 2022+1.4%
Jul 2022+1.5%
Aug 2022+13%
Sep 2022+4.0%
Oct 2022-0.07%
Nov 2022-7.7%
Dec 2022-7.4%
Jan 2023+5.6%2023
Feb 2023-10.0%
Mar 2023-0.45%
Apr 2023-1.0%
May 2023+16%
Jun 2023+0.32%
Jul 2023+0.97%
Aug 2023-2.8%
Sep 2023+13%
Oct 2023-2.4%
Nov 2023+12%
Dec 2023+2.3%
Jan 2024+1.6%2024
Feb 2024-12%
Mar 2024-4.1%
Apr 2024-4.8%
May 2024-8.9%
Jun 2024+27%
Jul 2024+3.8%
Aug 2024-3.6%
Sep 2024-16%
Oct 2024-4.2%
Nov 2024-6.9%
Dec 2024-2.2%
Jan 2025-8.8%2025
Feb 2025+4.0%
Mar 2025-9.1%
Apr 2025+1.8%
May 2025+9.1%
Jun 2025+18%
Jul 2025+8.8%
Aug 2025-0.79%
Sep 2025+53%
Oct 2025+14%
Nov 2025+11%
Dec 2025-4.4%
Jan 2026+4.5%2026
Feb 2026-1.8%
Mar 2026-7.5%
Apr 2026-0.44%
May 2026+2.3%
Jun 2026+3.6%
Jul 2026-35%
Aug 2026+17%
Sep 2026-26%
Oct 2026-3.8%
Ionis Pharmaceuticals Inc. returns by calendar month#
Every month of every year since 1992, one tick per year on a shared scale; the dark bar is the month's average. Total returns, dividends reinvested.
October 2026 so far: -3.83% — 19th of 35 Octobers since 1992 at the last close; the average October returned -1.0%.
| Month | −95%0+95% | Average | Median | Up | Best | Worst |
|---|---|---|---|---|---|---|
| Jan | +4.6% | +4.5% | 63% | +46.9% 1995 | -37.1% 2016 | |
| Feb | -1.6% | -7.7% | 34% | +80.8% 2000 | -25.2% 2003 | |
| Mar | -2.1% | -3.7% | 34% | +23.6% 2010 | -25.4% 1999 | |
| Apr | -0.0% | -1.6% | 40% | +54.5% 2003 | -38.4% 2014 | |
| May | +2.8% | -0.7% | 49% | +64.3% 1995 | -44.6% 2016 | |
| Jun | +3.6% | +1.4% | 60% | +56.8% 2000 | -22.6% 2006 | |
| Jul | -1.8% | -0.7% | 49% | +25.7% 2008 | -34.7% 2026 | |
| Aug | +3.6% | +2.3% | 54% | +36.2% 2001 | -39.6% 1998 | |
| Sep | +3.2% | -1.4% | 43% | +56.9% 1998 | -26.0% 2026 | |
| Oct | -1.0% | -1.7% | 38% | +28.0% 1993 | -38.6% 2012 | |
| Nov | +8.6% | +7.1% | 65% | +91.7% 1992 | -18.4% 2008 | |
| Dec | +0.8% | +2.5% | 59% | +25.0% 2004 | -60.0% 1999 |
Methodology#
Monthly returns are total returns (dividends reinvested), computed from IONS's split- and dividend-adjusted month-end closes. The table shows the most recent 120 months and the bar chart the most recent 60. See the year-by-year returns for the annual view. Past performance does not predict future returns; not investment advice.
FAQ#
- What is Ionis Pharmaceuticals Inc.'s average monthly return?
- Ionis Pharmaceuticals Inc. (IONS) has averaged about 1.69% per month, positive in roughly 49% of months. The best month was Nov 1992 (+91.7%) and the worst was Dec 1999 (-60.0%).
More on Ionis Pharmaceuticals Inc.
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