How much would $1,000 invested in IONS be worth today?

$1,000 invested in IONS on October 17, 2016 would be worth $1,487 on October 16, 2026, with dividends reinvested — 4.1% a year compounded (CAGR).

How far back does the IONS calculator go?

IONS data begins May 17, 1991, with a close every session. Pick any start and end date in that span — 35 years, 5 months of history.

Does this include dividends?

Yes. The default "dividends reinvested" view uses split- and dividend-adjusted closing prices — a standard total-return approximation that excludes taxes and fees. A price-only view (split-adjusted, no dividends) is also available.

If You Invested $1,000 in IONS: What It Would Be Worth Today

Share this page

IONS

$42.94-2.67%

as of close, Oct 16, 2026

☾ AH $42.94 -2.67%

Ionis Pharmaceuticals Inc.Stock · HealthcareNasdaq Composite 0.03%Russell 1000 0.02%Russell 3000 0.02%US Stock Market 0.02%

PeersMRNALLYMDTUNHJNJTMO

Your investment#

How much

All at once, on the start date

Pick start & end dates10 years

Start

Key dates

Start at a well-known dateRecentMarket topsMarket bottomsEvents

Bought at that day's close

End

Key dates

End at a well-known dateMarket topsMarket bottomsEvents

Latest close, Oct 16, 2026

Or drag the slider to set start and end dates

1991 to today, log scale

2008 crisisCovidDot-com bust

19952000200520102020Oct 2016Today

Options

Result#

$1,000Oct 17, 2016$1,487Oct 16, 20261.5×your money

$1,000 invested in IONS on October 17, 2016 was worth $1,487 on October 16, 2026, with dividends reinvested.

That’s 4.1% a year compounded (CAGR) over 10 years: 1.5 times your money.

Over the same dates the same $1,000 would be worth $4,208 in the S&P 500 and $6,511 in the Nasdaq-100: IONS trailed both the S&P 500 and the Nasdaq-100.

Price only$1,487if dividends were spent

Biggest fall−70.4%Apr 8, 2019 to Apr 8, 2025

At a flat 5% a year$1,629a savings account's rate

Gain$487on $1,000 put in

How this period ranks#

Better than 50% of all 306 periods of 10 years since 1991.

Your dates

−70%0%250%

Worst: −11.1% a year, Jun 1995 to Jun 2005Best: 34.6% a year, Apr 2005 to Apr 2015

One scale for every length, so longer periods bunch up. Point at a bar.

Growth of $1,000 in IONS, October 17, 2016 to October 16, 2026#

Your $1,000$Your buySame plan in the S&P 500The highA low

Lowest value$884 · Apr 2025Highest value$2,996 · Feb 2026$1,404 · May 2018$1,313 · Apr 2017$

$1,000$2,000$3,000$4,000$1,487

20182020202220242026

How far IONS was below its previous high. The biggest fall: −70.4% from Apr 8, 2019 to Apr 8, 2025, back to the high by Feb 6, 2026.

−70.4% from its high−51.0% from its high−37.1% from its high−31.2% from its high

high−70%

Your one buy. $1,000 on October 17, 2016, worth $1,487 on October 16, 2026. Pick Monthly or Yearly to see a plan's buys.

1.5×paid

What $1,000 would be worth on October 16, 2026, by start date#

Each point is the same amount invested that day and held to October 16, 2026, dividends reinvested. Above the line it made money.

Your start

$500$1,000$2,000$5,000$10k

1995200020052010201520202025

$1,000 invested in IONS, by year#

Started on each year's first close and held to Oct 16, 2026, dividends reinvested.

Started	Worth Oct 16, 2026	Multiple	A year (CAGR)	Same in the Nasdaq-100
2017	$907	0.91×	−1.0%	$6,344
2018	$872	0.87×	−1.5%	$4,742
2019	$799	0.80×	−2.8%	$4,812
2020	$705	0.71×	−5.0%	$3,420
2021	$756	0.76×	−4.7%	$2,373
2022	$1,317	1.3×	5.9%	$1,818
2023	$1,143	1.1×	3.6%	$2,741
2024	$812	0.81×	−7.2%	$1,789
2025	$1,238	1.2×	12.7%	$1,403
2026	$539	0.54×	—	$1,162

Methodology#

A buy is made at the start date's close, or the next session's when the market was closed that day, and valued at the end date's close; a monthly or yearly plan buys on the same day of each month or year. "Dividends reinvested" uses split- and dividend-adjusted closes (a standard total-return approximation; taxes and fees excluded). "Price-only" uses split-adjusted closes. IONS data begins May 17, 1991; values as of October 16, 2026 and refresh daily. The ranking compares month-end to month-end periods. Past performance does not predict future returns; not investment advice.

See the live IONS chart and fundamentals on the IONS quote page or the S&P 500 return calculator.

FAQ#

How much would $1,000 invested in IONS be worth today?: $1,000 invested in IONS on October 17, 2016 would be worth $1,487 on October 16, 2026, with dividends reinvested — 4.1% a year compounded (CAGR).
How far back does the IONS calculator go?: IONS data begins May 17, 1991, with a close every session. Pick any start and end date in that span — 35 years, 5 months of history.
Does this include dividends?: Yes. The default "dividends reinvested" view uses split- and dividend-adjusted closing prices — a standard total-return approximation that excludes taxes and fees. A price-only view (split-adjusted, no dividends) is also available.

IONS return calculator