Ionis Pharmaceuticals Inc. trailing returns
Ionis Pharmaceuticals Inc.'s 10-year return is +4.0% a year (CAGR) (+48.1% cumulative). How Ionis Pharmaceuticals Inc. (IONS) has performed over the last day, week, month and year, over 5, 10, 20 and 30 years, and since inception, through October 16, 2026 — price return and dividends side by side, with the worst drop inside each window.
Trailing returns by period#
To 2026-10-16. Price return + dividends = total return. Per year (CAGR) for windows of a year or more, with the cumulative total return beneath. Worst drop: the deepest fall in the price from a high inside the window, and when it bottomed.
| Period | Price | DivsDividends | Total | Worst drop |
|---|---|---|---|---|
| 1 day | -2.7% | +0.0% | -2.7% | — |
| 5 days | -5.2% | +0.0% | -5.2% | -6.4%Oct 13 |
| 1 month | -4.2% | +0.0% | -4.2% | -9.3%Oct 13 |
| YTD | -45.7% | +0.0% | -45.7% | -51.0%Oct 13 |
| 1 year | -41.2% | +0.0% | -41.2% | -51.0%Oct 2026 |
| 5 years | +4.1% | +0.0% | +4.1%+22.3% | -52.4%Apr 2025 |
| 10 years | +4.0% | +0.0% | +4.0%+48.1% | -70.4%Apr 2025 |
| 20 years | +8.4% | +0.0% | +8.4%+404.0% | -73.2%Jun 2016 |
| 30 years | +2.6% | +0.0% | +2.6%+117.4% | -91.7%Mar 2003 |
| Since inception (1991) | +4.2% | +0.0% | +4.2%+329.4% | -91.7%Mar 2003 |
Growth of IONS#
Actual level with dividends reinvested (solid); dashed lines are each window's constant-rate path from start to today.
- 5 years+4.1%/year · +22.3%
- 10 years+4.0%/year · +48.1%
- 20 years+8.4%/year · +404.0%
- 30 years+2.6%/year · +117.4%
- Since inception (1991)+4.2%/year · +329.4%
Methodology#
Trailing returns measure from the closest close about N years before the latest close (2026-10-16). Cumulative return is the total change over the window; annualized return is the compound annual growth rate (CAGR), shown for windows of a year or more. Price return is the change in IONS's closing price; total return reinvests dividends (from its split- and dividend-adjusted closes); the dividends column is the difference between the two. The worst drop is the largest fall in the closing price from a high to a later low inside the window, the way a drawdown is usually quoted. See the year-by-year returns for the calendar breakdown. Past performance does not predict future returns; not investment advice.
FAQ#
- What is Ionis Pharmaceuticals Inc.'s 10-year return?
- Over the last 10 years, Ionis Pharmaceuticals Inc. (IONS) returned about +4.0% a year annualized (+48.1% cumulative total return).
- What is Ionis Pharmaceuticals Inc.'s 20-year annualized return?
- Over the last 20 years, Ionis Pharmaceuticals Inc. (IONS) compounded at about +8.4% a year (+404.0% cumulative).
- What is Ionis Pharmaceuticals Inc.'s 30-year annualized return?
- Over the last 30 years, Ionis Pharmaceuticals Inc. (IONS) compounded at about +2.6% a year (+117.4% cumulative).
- What is Ionis Pharmaceuticals Inc.'s return since inception?
- Since 1991, Ionis Pharmaceuticals Inc. (IONS) has compounded at about +4.2% a year — +329.4% in total.