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VRTX
Vertex Pharmaceuticals IncorporatedStock · Healthcare · Nasdaq-100 0.6% · S&P 500 0.2%
$528.19+$12.64 (+2.45%)as of market close, Aug 18, 2026
☾ After hours:$528.19+0.00%7:57 PM ET
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VRTX trailing returns

Vertex Pharmaceuticals Incorporated's 10-year annualized return is +18.1% per year (+428.8% cumulative). How Vertex Pharmaceuticals Incorporated (VRTX) has performed over the last day, week, month and year, over 5, 10 and 20 years, and since inception, through August 18, 2026 — cumulative and annualized, with dividends on or off.

Trailing returns by period#

To 2026-08-18. Annualized (CAGR) for windows of a year or more.

PeriodPathAnnualizedCumulative
1 day+2.5%
1 week-0.3%
1 month+9.9%
YTD+16.5%
1 year
+35.5%
+35.5%
5 years
+21.6%
+166.2%
10 years
+18.1%
+428.8%
20 years
+14.9%
+1514.8%
Since inception (1991)
+14.6%
+11637.6%

Growth of VRTX#

Actual index level (solid); dashed lines are each window's constant-rate path from start to today.

5.010.020.050.010020050019952000200520102015202020255 yearsAug 2021 → Aug 2026+166.2%+21.6%/year10 yearsAug 2016 → Aug 2026+428.8%+18.1%/year20 yearsAug 2006 → Aug 2026+1514.8%+14.9%/yearSince inception (1991)Jul 1991 → Aug 2026+11637.6%+14.6%/year

Methodology#

Trailing returns measure from the closest close about N years before the latest close (2026-08-18). Cumulative return is the total change over the window; annualized return is the compound annual growth rate (CAGR), shown for windows of a year or more. Total return reinvests dividends (from VRTX's split- and dividend-adjusted closes); price return excludes them. See the year-by-year returns for the calendar breakdown. Past performance does not predict future returns; not investment advice.

See also: S&P 500 · Nasdaq-100 · Dow Jones · Russell 2000 · US Bond Market · Gold · Silver · Bitcoin · Ethereum

FAQ#

What is Vertex Pharmaceuticals Incorporated's 10-year return?
Over the last 10 years, Vertex Pharmaceuticals Incorporated (VRTX) returned about +18.1% a year annualized (+428.8% cumulative total return).
What is Vertex Pharmaceuticals Incorporated's 20-year annualized return?
Over the last 20 years, Vertex Pharmaceuticals Incorporated (VRTX) compounded at about +14.9% a year (+1514.8% cumulative).
What is Vertex Pharmaceuticals Incorporated's return since inception?
Since 1991, Vertex Pharmaceuticals Incorporated (VRTX) has compounded at about +14.6% a year — +11637.6% in total.