PRAX — Praxis Precision Medicines Inc. stock price and chart

Share this page

PRAX

$291.23+3.64%

as of close, Sep 30, 2026

☾ AH $291.23 +3.64%

Praxis Precision Medicines Inc.Stock · Health CareRussell 2000 0.3%Nasdaq Composite 0.02%US Stock Market 0.01%Russell 3000 0.01%

PeersMRNALLYUNHJNJMRKTMO

Technical analysis2

Overlay lines0

Addendum charts0

Available history since Oct 20, 2020

VolumeS

20202022202320252026

100.0200.0300.0400.0500.0600.0700.0800.0900.0010.0M$291.23

2026-09-30

Price$291.23

MA20$329.75

MA50$320.85

Vol710.5K

What would $1,000 invested in PRAX be worth today? →

PRAX returns: By year · By month · By week · Trailing

Key stats

Price data

Price: $291.23
Change YTD: -1.19%
Next earnings: Nov 4, 2026
Market cap: 8.1B2020-12 31.8B2026-09 8.1B-74.5% over the window
Enterprise value: 6.7B
Shares outstanding: 27.9M2019-12 1.6M2026-06 27.9M+1621.5% over the window
52W low: $50.31
52W high: $392.70
From 52W high: -25.84%
From 52W low: +478.87%
52W range: 70%
Beta: 2.76

Volume

Rel volume: 1.72×
30D volume: 413.4K
30D $ vol: 133.7M

Fundamentals

EPS (ttm): -$12.862020-12 -$7.862026-06 -$12.86+63.6% over the window
FCF (ttm): -305.4M2019-12 -33.5M2026-06 -305.4M+811.0% over the window
FCF/share: -$10.942019-12 -$20.672026-06 -$10.94-47.1% over the window
Book value/share: $48.032019-12 -$49.952026-06 $48.03-196.2% over the window
ROE: -25.29%2020-12 -21.5%2026-06 -25.3%+17.6% over the window
ROA: -24.40%2019-12 -74.5%2026-06 -24.4%-67.2% over the window
Current ratio: 15.732019-12 6.672026-06 15.73+135.8% over the window

Growth (CAGR, ttm) · 10Y

Shares: +32.69%2025-06-30 → 2026-06-3021M → 27.9M (+32.7% total)-39.88%2023-06-30 → 2026-06-30128.5M → 27.9M (-78.3% total)-8.99%2021-06-30 → 2026-06-3044.7M → 27.9M (-37.6% total)n/a

Per-share growth (CAGR, ttm) · 10Y

Book value/share: +150.23%2025-06-30 → 2026-06-30$19.21 → $48.03 (+150.1% total)+287.97%2023-06-30 → 2026-06-30$0.82 → $48.03 (+5745.2% total)+45.12%2021-06-30 → 2026-06-30$7.46 → $48.03 (+543.4% total)n/a
Price: +450.13%2025-09-30 → 2026-09-30$53.00 → $291.23 (+449.5% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.+124.55%2023-09-29 → 2026-09-30$25.65 → $291.23 (+1035.4% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.+0.98%2021-09-30 → 2026-09-30$277.35 → $291.23 (+5.0% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.n/a
Total return: +450.13%2025-09-30 → 2026-09-30$53.00 → $291.23 (+449.5% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.+124.55%2023-09-29 → 2026-09-30$25.65 → $291.23 (+1035.4% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.+0.98%2021-09-30 → 2026-09-30$277.35 → $291.23 (+5.0% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.n/a

Fundamentals end at the last reported quarter; price and total return end at the latest close.

Valuation

P/E (ttm)Price ÷ TTM diluted EPS. Net income carries everything below the operating line, including one-off gains. Negative when the trailing year lost money.: -22.6×2020-12 -515.032026-09 -23.98-95.3% over the window
Fwd P/E: -31.3×
P/B (mrq)Market cap ÷ stockholders' equity at the most recent quarter end.: 6.1×2020-12 110.762026-09 6.06-94.5% over the window
FCF yield (ttm)TTM free cash flow ÷ market cap — the inverse of P/FCF.: -3.76%2020-12 -0.2%2026-06 -3.3%+1876.7% over the window
Buyback yield (realized, 1y)1 − shares_at(2026-06-30) ÷ shares_at(2025-06-30) = 1 − 27.9M ÷ 21.0M. Point-in-time share counts from the company's own SEC filings (the same count at both ends), published only when the cash flow statement shows repurchases inside that window. A falling price can't inflate it; negative means net dilution.: -32.69%
Shareholder yield (realized, 1y)Buyback leg + dividend leg: shares retired over the year (-32.69%) + dividends paid over that year ($0) ÷ market_cap_at(2025-06-30) ($885M). Both legs are measured against the start of the window, so a payout can't shrink its own denominator.: -32.69%
Buyback yield (cash, ttm)Buybacks net of issuance over the trailing twelve months ($0) ÷ today's market cap ($8.1B). Dollars SPENT over what the company is worth NOW — a stock that fell after buying reads high.: 0.00%2020-12 0.0%2026-06 0.0%
Shareholder yield (cash, ttm)(TTM buybacks net of issuance $0 + TTM dividends $0) ÷ today's market cap ($8.1B). Same caveat as the cash buyback yield.: 0.00%2020-12 0.0%2026-06 0.0%

Vs own 10Y history

P/B: 29th

Bar = where today’s multiple sits in PRAX’s own 10-year range:near a decade-low (cheap)→near a decade-high (rich).

Performance · price return · as of 2026-09-30

+3.64%

+3.23%

-15.52%

-13.01%

YTD

-1.19%

+449.49%

+5.00%

Financial statements

Open full PRAX financials →

Loading financial statements…

Ticker	Name	1M	1D
NVS	Novartis AG	-7.31%	-2.15%
NVO	Novo Nordisk A/S	-16.88%	-1.04%
SNY	Sanofi ADS	-8.01%	+1.20%
GSK	GSK plc American Depositary Shares (Each representing two Ordinary Shares)	-5.21%	-2.39%
NTRA	Natera Inc.	+26.68%	-0.29%
ARGX	argenx SE American Depositary Shares	-6.28%	-1.21%
TAK	Takeda Pharmaceutical Company Limited American Depositary Shares (each representing 1/2 of a share of Common Stock)	+0.89%	-1.73%
TEVA	Teva Pharmaceutical Industries Limited American Depositary Shares	+8.67%	-0.53%

PRAX — Praxis Precision Medicines Inc. price, chart and key statistics