PRAX — Praxis Precision Medicines Inc. price, chart and key statistics

Price data

Price

$328.13

YTD price return

+11.33%

YTD total return

+11.33%

Market cap

9.2B2020-12 2.1B2026-11 9.2B+331.5% over the window

Enterprise value

7.9B

Shares outstanding

28M2019-12 108.1K2026-09 28M+25751.1% over the window

52W low

$160.11

52W high

$392.70

From 52W high

-16.44%

From 52W low

+104.94%

52W range

72%$160–$393

Beta

2.76

Volume

Rel volume

0.68×

30D volume

514.5K

30D $ vol

143.5M

Insider trading

Insider net 1WNo open-market insider purchase or sale with a transaction date in the last 7 days, as filed on Form 4.

none

Insider net 1MNo open-market insider purchase or sale with a transaction date in the last 30 days, as filed on Form 4.

none

Insider net 3MNo open-market insider purchase or sale with a transaction date in the last 91 days, as filed on Form 4.

none

Insider net 1Y0 insider-days of buying (no priced lot) and 1 of selling ($3.6M) in the last 365 days, by transaction date, open-market transactions only — awards, exercises, tax withholding and employee-plan purchases are not counted. A Form 4 is filed within two business days of the trade, so the newest days may not be in yet.

−$3.6M

Form 4 transactions by trade date, as filed; latest on file 2026-06-24.

Fundamentals

EPS (ttm)

-$12.762020-12 -$117.902026-09 -$12.76-89.2% over the window

FCF (ttm)

-323.6M2019-12 -33.5M2026-09 -323.6M+865.4% over the window

FCF/share

-$11.582019-12 -$310.042026-09 -$11.58-96.3% over the window

Book value/share

$45.062019-12 -$749.202026-09 $45.06-106.0% over the window

ROE

-28.54%2020-12 -21.5%2026-09 -28.5%+32.7% over the window

ROA

-27.39%2019-12 -74.5%2026-09 -27.4%-63.2% over the window

Current ratio

14.532019-12 6.672026-09 14.53+117.7% over the window

Growth (CAGR, ttm) · 10Y

Shares

+11.78%2025-09-30 → 2026-09-3025M → 28M (+11.8% total)+48.29%2023-09-30 → 2026-09-308.6M → 28M (+226.2% total)+56.37%2021-09-30 → 2026-09-303M → 28M (+834.7% total)n/a

Per-share growth (CAGR, ttm) · 10Y

Book value/share

+228.32%2025-09-30 → 2026-09-30$13.74 → $45.06 (+228.1% total)+64.48%2023-09-30 → 2026-09-30$10.12 → $45.06 (+345.1% total)-14.56%2021-09-30 → 2026-09-30$98.96 → $45.06 (-54.5% total)n/a

Price

+84.34%2025-11-13 → 2026-11-13$178.08 → $328.13 (+84.3% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.+192.89%2023-11-13 → 2026-11-13$13.05 → $328.13 (+2414.4% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.+1.49%2021-11-12 → 2026-11-13$304.80 → $328.13 (+7.7% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.n/a

Total return

+84.34%2025-11-13 → 2026-11-13$178.08 → $328.13 (+84.3% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.+192.89%2023-11-13 → 2026-11-13$13.05 → $328.13 (+2414.4% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.+1.49%2021-11-12 → 2026-11-13$304.80 → $328.13 (+7.7% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.n/a

Fundamentals end at the last reported quarter; price and total return end at the latest close.

Valuation

P/E (ttm)Price ÷ TTM diluted EPS. Net income carries everything below the operating line, including one-off gains. Negative when the trailing year lost money.

-25.7×2020-12 -34.342026-11 -25.48-25.8% over the window

Fwd P/E

-34.7×

P/B (mrq)Market cap ÷ stockholders' equity at the most recent quarter end.

7.3×2020-12 7.382026-11 7.27-1.5% over the window

FCF yield (ttm)TTM free cash flow ÷ market cap — the inverse of P/FCF.

-3.53%2020-12 -2.5%2026-09 -4.0%+60.4% over the window

Buyback yield (realized, 1y)1 − shares_at(2026-09-30) ÷ shares_at(2025-09-30) = 1 − 28.0M ÷ 25.0M. Point-in-time share counts from the company's own SEC filings (the same count at both ends), published only when the cash flow statement shows repurchases inside that window. A falling price can't inflate it; negative means net dilution.

-11.78%

Shareholder yield (realized, 1y)Buyback leg + dividend leg: shares retired over the year (-11.78%) + dividends paid over that year ($0) ÷ market_cap_at(2025-09-30) ($1.3B). Both legs are measured against the start of the window, so a payout can't shrink its own denominator.

-11.78%

Buyback yield (cash, ttm)Buybacks net of issuance over the trailing twelve months ($0) ÷ today's market cap ($9.2B). Dollars SPENT over what the company is worth NOW — a stock that fell after buying reads high.

0.00%2020-12 0.0%2026-09 0.0%

Shareholder yield (cash, ttm)(TTM buybacks net of issuance $0 + TTM dividends $0) ÷ today's market cap ($9.2B). Same caveat as the cash buyback yield.

0.00%2020-12 0.0%2026-09 0.0%

Vs own 10Y history

P/B

88th