MDGL — Madrigal Pharmaceuticals Inc. price, chart and key statistics

Price data

Price

$499.40

Change YTD

-14.24%

Next earnings

Nov 3, 2026

Market cap

11.5B2016-12 172.4M2026-10 11.5B+6593.4% over the window

Enterprise value

10.8B

Shares outstanding

23.1M2016-06 3.9M2026-06 23.1M+486.8% over the window

52W low

$393.61

52W high

$615.00

From 52W high

-18.80%

From 52W low

+26.88%

52W range

48%

Beta

-0.97

Volume

Rel volume

1.29×

30D volume

223.7K

30D $ vol

117.6M

Insider trading

Insider net 1WNo open-market insider purchase or sale with a transaction date in the last 7 days, as filed on Form 4.

none

Insider net 1M0 insider-days of buying (no priced lot) and 2 of selling ($6.2M) in the last 30 days, by transaction date, open-market transactions only — awards, exercises, tax withholding and employee-plan purchases are not counted. A Form 4 is filed within two business days of the trade, so the newest days may not be in yet.

−$6.2M

Insider net 3M0 insider-days of buying (no priced lot) and 4 of selling ($7.9M) in the last 91 days, by transaction date, open-market transactions only — awards, exercises, tax withholding and employee-plan purchases are not counted. A Form 4 is filed within two business days of the trade, so the newest days may not be in yet.

−$7.9M

Insider net 1Y0 insider-days of buying (no priced lot) and 20 of selling ($40.2M) in the last 365 days, by transaction date, open-market transactions only — awards, exercises, tax withholding and employee-plan purchases are not counted. A Form 4 is filed within two business days of the trade, so the newest days may not be in yet.

−$40.2M

Form 4 transactions by trade date, as filed; latest on file 2026-09-11.

Fundamentals

Sales (ttm)

1.3B2017-12 02026-06 1.3B

Sales/share

$55.572017-12 $0.002026-06 $55.57

EPS (ttm)

-$11.262020-12 -$13.092026-06 -$11.26-14.0% over the window

FCF (ttm)

-206.3M2016-09 -13.4M2026-06 -206.3M+1434.5% over the window

FCF/share

-$8.932016-09 -$1.162026-06 -$8.93+668.4% over the window

Book value/share

$22.672016-06 $10.562026-06 $22.67+114.7% over the window

Net margin

-25.32%2024-06 -3487.1%2026-06 -25.3%-99.3% over the window

ROE

-62.07%2016-06 -40.7%2026-06 -62.1%+52.5% over the window

ROA

-26.12%2016-06 -37.7%2026-06 -26.1%-30.7% over the window

Debt / equity

0.65×2021-12 0.002026-06 0.65

Current ratio

3.202016-06 13.332026-06 3.20-76.0% over the window

Growth (CAGR, ttm) · 10Y

Sales

+149.20%2025-06-30 → 2026-06-30515.5M → 1.3B (+149.0% total)n/an/an/a

Shares

+3.66%2025-06-30 → 2026-06-3022.3M → 23.1M (+3.7% total)+7.74%2023-06-30 → 2026-06-3018.5M → 23.1M (+25.1% total)+6.84%2021-06-30 → 2026-06-3016.6M → 23.1M (+39.2% total)+19.36%2016-06-30 → 2026-06-303.9M → 23.1M (+486.8% total)

Per-share growth (CAGR, ttm) · 10Y

Sales/share

+140.40%2025-06-30 → 2026-06-30$23.13 → $55.57 (+140.3% total)n/an/an/a

Book value/share

-27.42%2025-06-30 → 2026-06-30$31.23 → $22.67 (-27.4% total)+59.32%2023-06-30 → 2026-06-30$5.60 → $22.67 (+304.5% total)+6.81%2021-06-30 → 2026-06-30$16.30 → $22.67 (+39.0% total)+7.94%2016-06-30 → 2026-06-30$10.56 → $22.67 (+114.7% total)

Price

+11.07%2025-10-02 → 2026-10-02$449.64 → $499.40 (+11.1% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.+51.58%2023-10-02 → 2026-10-02$143.36 → $499.40 (+248.4% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.+44.05%2021-10-01 → 2026-10-02$80.45 → $499.40 (+520.8% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.+44.37%2016-09-30 → 2026-10-02$12.68 → $499.40 (+3838.5% total)Price appreciation from split-adjusted daily closes, excluding dividends; endpoints are exact trading-day anniversaries of the latest close.

Total return

+11.07%2025-10-02 → 2026-10-02$449.64 → $499.40 (+11.1% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.+51.58%2023-10-02 → 2026-10-02$143.36 → $499.40 (+248.4% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.+44.05%2021-10-01 → 2026-10-02$80.45 → $499.40 (+520.8% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.+44.37%2016-09-30 → 2026-10-02$12.68 → $499.40 (+3838.5% total)Total return with dividends reinvested (adjusted daily closes); endpoints are exact trading-day anniversaries of the latest close. The gap against the Price row is the dividend contribution.

Fundamentals end at the last reported quarter; price and total return end at the latest close.

Valuation

P/E (ttm)Price ÷ TTM diluted EPS. Net income carries everything below the operating line, including one-off gains. Negative when the trailing year lost money.

-44.4×2016-12 -5.912026-10 -35.49+500.7% over the window

Fwd P/E

53.0×

P/S (ttm)Market cap ÷ TTM revenue.

9.0×2016-12 1172.762026-10 8.99-99.2% over the window

P/B (mrq)Market cap ÷ stockholders' equity at the most recent quarter end.

22.0×2016-12 4.592026-10 22.03+380.4% over the window

EV/Sales (ttm)

8.4×

FCF yield (ttm)TTM free cash flow ÷ market cap — the inverse of P/FCF.

-1.79%2016-09 -7.8%2026-06 -1.7%-78.7% over the window

Buyback yield (realized, 1y)1 − shares_at(2026-06-30) ÷ shares_at(2025-06-30) = 1 − 23.1M ÷ 22.3M. Point-in-time share counts from the company's own SEC filings (the same count at both ends), published only when the cash flow statement shows repurchases inside that window. A falling price can't inflate it; negative means net dilution.

-3.66%

Shareholder yield (realized, 1y)Buyback leg + dividend leg: shares retired over the year (-3.66%) + dividends paid over that year ($0) ÷ market_cap_at(2025-06-30) ($6.7B). Both legs are measured against the start of the window, so a payout can't shrink its own denominator.

-3.66%

Buyback yield (cash, ttm)Buybacks net of issuance over the trailing twelve months ($0) ÷ today's market cap ($11.5B). Dollars SPENT over what the company is worth NOW — a stock that fell after buying reads high.

0.00%2016-09 21.4%2026-06 0.0%-100.0% over the window

Shareholder yield (cash, ttm)(TTM buybacks net of issuance $0 + TTM dividends $0) ÷ today's market cap ($11.5B). Same caveat as the cash buyback yield.

0.00%2016-09 21.4%2026-06 0.0%-100.0% over the window

Vs own 10Y history

P/S

0th

P/B

83rd