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DNLI
$17.61-3.98%
as of close, Oct 16, 2026
☾ AH $17.61 -3.98%
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Denali Therapeutics Inc. monthly returns

Denali Therapeutics Inc. has averaged 1.68% per month, positive in 49% of months. Month-by-month returns for Denali Therapeutics Inc. (DNLI) below, through October 16, 2026 — the table lists the most recent months; the bar chart plots the last 5 years.

Average month
+1.7%
106 months
Best month
+55.9%
Aug 2018
Worst month
-34.9%
Jul 2021
Positive months
49%
of all months

Denali Therapeutics Inc. monthly returns#

Denali Therapeutics Inc. total return by month
MonthTotal return
Oct 2026
-14.8%
Sep 2026
-13.0%
Aug 2026
+3.2%
Jul 2026
-10.5%
Jun 2026
+22.2%
May 2026
+12.4%
Apr 2026
-2.5%
Mar 2026
-9.3%
Feb 2026
-2.6%
Jan 2026
+31.7%
Dec 2025
-15.2%
Nov 2025
+19.6%
Oct 2025
+12.1%
Sep 2025
-4.9%
Aug 2025
+10.4%
Jul 2025
-1.1%
Jun 2025
+5.7%
May 2025
-20.5%
Apr 2025
+22.5%
Mar 2025
-17.9%
Feb 2025
-28.9%
Jan 2025
+14.3%
Dec 2024
-18.5%
Nov 2024
-3.7%
Oct 2024
-10.9%
Sep 2024
+19.2%
Aug 2024
+0.3%
Jul 2024
+5.0%
Jun 2024
+25.1%
May 2024
+20.2%
Apr 2024
-24.8%
Mar 2024
+3.7%
Feb 2024
+23.5%
Jan 2024
-25.4%
Dec 2023
+15.9%
Nov 2023
-1.6%
Oct 2023
-8.7%
Sep 2023
-10.7%
Aug 2023
-18.8%
Jul 2023
-3.7%
Jun 2023
-2.3%
May 2023
+21.7%
Apr 2023
+7.8%
Mar 2023
-15.1%
Feb 2023
-10.3%
Jan 2023
+8.8%
Dec 2022
-12.8%
Nov 2022
+11.3%
Oct 2022
-6.5%
Sep 2022
+10.9%
Aug 2022
-18.7%
Jul 2022
+15.6%
Jun 2022
+21.2%
May 2022
+2.1%
Apr 2022
-26.0%
Mar 2022
-1.2%
Feb 2022
-4.9%
Jan 2022
-23.3%
Dec 2021
-3.6%
Nov 2021
-4.3%
Oct 2021
-4.2%
Sep 2021
-5.2%
Aug 2021
+4.3%
Jul 2021
-34.9%
Jun 2021
+23.4%
May 2021
+5.2%
Apr 2021
+5.8%
Mar 2021
-20.5%
Feb 2021
+4.8%
Jan 2021
-18.2%
Dec 2020
+37.4%
Nov 2020
+42.5%
Oct 2020
+19.4%
Sep 2020
+12.3%
Aug 2020
+36.2%
Jul 2020
-3.1%
Jun 2020
-13.1%
May 2020
+27.3%
Apr 2020
+24.8%
Mar 2020
-11.4%
Feb 2020
-14.6%
Jan 2020
+33.0%
Dec 2019
-2.1%
Nov 2019
+13.5%
Oct 2019
+2.3%
Sep 2019
-14.9%
Aug 2019
-15.7%
Jul 2019
+2.8%
Jun 2019
+8.9%
May 2019
-22.1%
Apr 2019
+5.4%
Mar 2019
+6.7%
Feb 2019
+14.2%
Jan 2019
-7.7%
Dec 2018
+7.8%
Nov 2018
+32.5%
Oct 2018
-33.4%
Sep 2018
+10.7%
Aug 2018
+55.9%
Jul 2018
-17.4%
Jun 2018
-20.7%
May 2018
+4.1%
Apr 2018
-6.1%
Mar 2018
-14.0%
Feb 2018
-1.6%
Jan 2018
+48.7%

Monthly total return (since Nov 2021)#

Denali Therapeutics Inc. returns by calendar month#

Every month of every year since 2018, one tick per year on a shared scale; the dark bar is the month's average. Total returns, dividends reinvested.

October 2026 so far: -14.80% — 8th of 9 Octobers since 2018 at the last close; the average October returned -3.7%.

Denali Therapeutics Inc. returns by calendar month since 2018
Month−60%0+60%AverageUp
Jan+6.9%56%
Feb-2.3%33%
Mar-8.8%22%
Apr+0.8%56%
May+5.6%78%
Jun+7.8%67%
Jul-5.3%33%
Aug+6.4%67%
Sep+0.5%44%
OctOctober 2026 so far: -14.8%-3.7%38%
Nov+13.7%63%
Dec+1.1%38%

Methodology#

Monthly returns are total returns (dividends reinvested), computed from DNLI's split- and dividend-adjusted month-end closes. The table shows the most recent 120 months and the bar chart the most recent 60. See the year-by-year returns for the annual view. Past performance does not predict future returns; not investment advice.

FAQ#

What is Denali Therapeutics Inc.'s average monthly return?
Denali Therapeutics Inc. (DNLI) has averaged about 1.68% per month, positive in roughly 49% of months. The best month was Aug 2018 (+55.9%) and the worst was Jul 2021 (-34.9%).

More on Denali Therapeutics Inc.