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DNLI
$17.61-3.98%
as of close, Oct 16, 2026
☾ AH $17.61 -3.98%
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Denali Therapeutics Inc. total returns by year (including dividends)

As of market close, Oct 16, 2026

Denali Therapeutics Inc. total returns by year (2018–2026)#

Denali Therapeutics Inc. annual returns by year
YearTotal return
2026YTD
+6.7%
2025
-19.0%
2024
-5.0%
2023
-22.8%
2022
-37.6%
2021
-46.8%
2020
+380.8%
2019
-15.7%
2018
+32.1%
Annualized
+1.4%
2018–2026
Average year
+33.2%
8 full years
Best year
+380.8%
2020
Worst year
-46.8%
2021
Positive years
2/8
25% up

Total return by period#

Annual

Methodology#

Total returns, dividends reinvested, measured on DNLI. Annualized return is the compound annual growth rate; the current year is year-to-date. Past performance does not predict future returns.

FAQ#

What is Denali Therapeutics Inc.'s average annual return?
Since 2018, Denali Therapeutics Inc. (DNLI) has returned about 1.4% a year (the compound annual growth rate) and an average calendar-year return of 33.2%.
What were Denali Therapeutics Inc.'s best and worst years?
Over 2018–2026, the best year was 2020 (+380.8%) and the worst was 2021 (-46.8%).
How often is Denali Therapeutics Inc. up in a year?
2 of the 8 full years since 2018 were positive — about 25% of the time.

More on Denali Therapeutics Inc.