ALNY
$246.74-2.89%
as of close, Sep 30, 2026
☾ AH $246.74 -2.89%
Alnylam Pharmaceuticals Inc.Stock · Health CareNasdaq-100 0.2%Nasdaq Composite 0.09%Russell 1000 0.06%US Stock Market 0.06%Russell 3000 0.06%MSCI World 0.04%MSCI ACWI 0.03%
ALNY financial statements
The full income statement, balance sheet, and cash-flow statement for Alnylam Pharmaceuticals Inc. (ALNY), plus valuation ratios — straight from SEC filings. Switch between annual, quarterly, and trailing-twelve-month figures, pick how far back to look, and flip the time order. Every line has a trend sparkline.
Shares outstanding (point-in-time)
2024-06 128.4M2024-09 129.0M2024-12 129.5M2025-03 130.4M2025-06 131.1M2025-09 132.1M2025-12 132.6M2026-03 133.5M2026-06 133.8M+4.2% over 8 periods
SEC-filed end-of-period counts (cover pages and balance sheets, split-adjusted) — the series realized buyback yield is computed from. The weighted-average share lines in the statements below lag these by design: an average over the year sits near the midpoint of an ongoing buyback.
As-reported fiscal years.
| Line item | Trend | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|---|
| Income Statement | as ofDec 31 ’25 | as ofDec 31 ’24 | as ofDec 31 ’23 | as ofDec 31 ’22 | as ofDec 31 ’21 | |
| Revenue | 3.71B+65.2% | 2.25B+23.0% | 1.83B+76.2% | 1.04B+22.9% | 844M+71.3% | |
| Cost of revenue | 677M+120.9% | 307M+14.3% | 268M+91.3% | 140M+21.9% | 115M+55.0% | |
| Research & development | 1.32B+17.2% | 1.13B+12.1% | 1.00B+13.7% | 883M+11.5% | 792M+21.0% | |
| Selling, general & administrative | 1.21B+24.1% | 976M+22.6% | 796M+3.2% | 771M+24.2% | 621M+5.5% | |
| Operating income | 502M+383.6% | -177M+37.3% | -282M+64.1% | -785M-10.8% | -709M+14.5% | |
| Interest expense | 253M+78.1% | 142M+17.0% | 121M-22.3% | 156M+9.1% | 143M+69.3% | |
| Interest & investment income | 111M-8.6% | 122M+27.7% | 95.6M+285.2% | 24.8M+1471.1% | 1.58M-86.6% | |
| Other non-operating income | 5.20M+102.9% | -181M-43.7% | -126M+6.3% | -134M-6445.1% | -2.05M-103.6% | |
| Gain (loss) on equity securities | -2.31M+23.7% | -3.02M+82.2% | -16.9M+49.1% | -33.3M-159.8% | 55.7M+3.1% | |
| Pre-tax income | 323M+185.6% | -377M+13.0% | -434M+61.5% | -1.13B-32.3% | -852M+0.4% | |
| Income tax | 9.40M+109.5% | -99.2M-1575.4% | 6.72M+61.5% | 4.16M+512.2% | 680K-74.6% | |
| Net income | 314M+212.8% | -278M+36.8% | -440M+61.1% | -1.13B-32.6% | -853M+0.6% | |
| $2.33+206.9% | -$2.18+38.1% | -$3.52+62.2% | -$9.30-29.2% | -$7.20+3.5% | ||
| EPS (basic) | $2.39+209.6% | -$2.18+38.1% | -$3.52+62.2% | -$9.30-29.2% | -$7.20+3.5% | |
| Weighted-avg shares (basic) | 131M+2.6% | 128M+2.2% | 125M+2.6% | 122M+2.7% | 118M+3.0% | |
| Weighted-avg shares (diluted) | 135M+5.5% | 128M+2.2% | 125M+2.6% | 122M+2.7% | 118M+3.0% | |
| Balance Sheet | as ofDec 31 ’25 | as ofDec 31 ’24 | as ofDec 31 ’23 | as ofDec 31 ’22 | as ofDec 31 ’21 | |
| 4.05B+22.9% | 3.30B+10.5% | 2.98B+10.8% | 2.69B-4.1% | 2.81B+7.4% | ||
| Cash & equivalents | 1.66B+71.5% | 966M+18.9% | 813M-6.2% | 866M+5.7% | 820M+65.1% | |
| Accounts receivable | 778M+91.8% | 405M+23.6% | 328M+37.7% | 238M+19.8% | 199M+93.9% | |
| Inventory | 82.7M+5.4% | 78.5M-11.9% | 89.1M-30.9% | 129M+49.3% | 86.4M+14.8% | |
| Prepaid expenses | 282M+141.0% | 117M-7.5% | 126M-4.9% | 133M+50.9% | 88.1M+40.3% | |
| 4.97B+17.1% | 4.24B+10.7% | 3.83B+8.0% | 3.55B-2.7% | 3.64B+6.9% | ||
| Property, plant & equipment | 513M+2.1% | 503M-4.4% | 526M+0.5% | 523M+4.3% | 502M+7.9% | |
| Operating lease right-of-use | 195M+2.0% | 191M-4.3% | 200M-7.2% | 215M-7.1% | 232M-4.1% | |
| Deferred tax assets | 126M+7.8% | 117M+1056.9% | 10.1M | — | — | |
| Other non-current assets | 59.5M-9.0% | 65.3M+5.5% | 61.9M-6.3% | 66.1M+9.8% | 60.2M+33.7% | |
| 1.47B+23.6% | 1.19B+22.6% | 968M+26.0% | 768M+10.4% | 696M+18.9% | ||
| Accounts payable | 116M+30.9% | 88.4M+59.3% | 55.5M-43.4% | 98.1M+33.6% | 73.4M+41.3% | |
| Accrued liabilities | 1.08B+36.1% | 794M+11.3% | 713M+30.7% | 545M+38.0% | 395M+11.0% | |
| Deferred revenue | 4.84M-91.3% | 55.5M-46.0% | 103M+144.0% | 42.1M-71.8% | 149M+17.5% | |
| Current lease liability | 45.5M+8.7% | 41.9M+0.9% | 41.5M-1.1% | 42.0M+3.5% | 40.5M+10.0% | |
| 4.18B+0.1% | 4.17B+3.0% | 4.05B+9.3% | 3.70B+21.3% | 3.06B+27.8% | ||
| Long-term debt | — | — | — | — | 676M+253.3% | |
| Deferred revenue (non-current) | — | 0.00-100.0% | 188M-2.9% | 194M+27.2% | 152M-32.3% | |
| Non-current lease liability | 225M-1.9% | 230M-5.6% | 243M-7.0% | 261M-7.1% | 281M-4.0% | |
| Operating lease liability (total) | 271M-0.3% | 271M-4.6% | 285M-6.2% | 303M-5.8% | 322M-2.4% | |
| Other non-current liabilities | 7.59M+52.8% | 4.97M-98.4% | 308M+45.1% | 213M+114.8% | 99.0M+161.1% | |
| 789M+1076.3% | 67.1M+130.4% | -221M-39.5% | -158M-126.9% | 588M-42.1% | ||
| Preferred stock | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Common stock | 1.32M+2.4% | 1.29M+2.7% | 1.26M+1.5% | 1.24M+3.2% | 1.20M+3.3% | |
| Additional paid-in capital | 7.51B+1.7% | 7.39B+8.5% | 6.81B+5.5% | 6.45B+6.5% | 6.06B+7.3% | |
| Retained earnings | -6.70B+8.0% | -7.29B-4.0% | -7.01B-6.7% | -6.57B-20.8% | -5.44B-18.6% | |
| Accumulated other comprehensive income | -20.1M+41.8% | -34.5M-47.7% | -23.4M+47.7% | -44.7M-34.3% | -33.3M+23.8% | |
| Total liabilities & equity | 4.97B+17.1% | 4.24B+10.7% | 3.83B+8.0% | 3.55B-2.7% | 3.64B+6.9% | |
| Common shares issued | 132M+2.4% | 129M+2.8% | 126M+1.5% | 124M+3.1% | 120M+3.2% | |
| Common shares outstanding | 132M+2.4% | 129M+2.8% | 126M+1.5% | 124M+3.1% | 120M+3.2% | |
| Shares outstanding (cover) | 133M+2.4% | 129M+2.8% | 126M+1.5% | 124M+3.3% | 120M+2.7% | |
| Cash Flow | as ofDec 31 ’25 | as ofDec 31 ’24 | as ofDec 31 ’23 | as ofDec 31 ’22 | as ofDec 31 ’21 | |
| 524M+6405.1% | -8.31M-108.0% | 104M+119.2% | -541M+15.6% | -642M-4.3% | ||
| Depreciation & amortization | 55.7M-1.8% | 56.7M+4.8% | 54.1M+21.6% | 44.5M-6.5% | 47.6M+36.8% | |
| Share-based compensation | 348M+28.0% | 272M+22.7% | 222M-3.9% | 231M+39.2% | 166M+18.5% | |
| Deferred income taxes | -2.20M+97.9% | -107M-14873.6% | -713K+50.2% | -1.43M+48.2% | -2.77M+14.0% | |
| Change in receivables | 360M+315.9% | 86.5M-1.6% | 87.9M+92.9% | 45.6M-55.2% | 102M+81.0% | |
| Change in inventory | -8.47M+37.6% | -13.6M+26.0% | -18.4M-153.8% | 34.1M+29.2% | 26.4M-25.4% | |
| Other operating activities | -29.8M+23.7% | -39.0M-1538.8% | -2.38M-1244.1% | -177K-100.9% | 19.2M+424.7% | |
| 436M+473.4% | -117M+65.3% | -336M-298.6% | 169M+162.0% | -273M+37.2% | ||
| Capital expenditure | 58.7M+71.2% | 34.3M-44.9% | 62.2M-13.7% | 72.1M-5.6% | 76.4M+8.5% | |
| Free cash flow | 465M+1192.7% | -42.6M-201.5% | 41.9M+106.8% | -613M+14.6% | -718M-4.8% | |
| Acquisitions | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Other investing activities | 2.15M+1737.6% | 117K-97.4% | 4.44M-5.5% | 4.69M+11.8% | 4.20M-20.8% | |
| -305M-203.8% | 294M+70.9% | 172M-59.6% | 426M-65.9% | 1.25B+25.3% | ||
| Long-term debt issued | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Long-term debt repaid | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Common stock issued | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Common stock repurchased | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| Dividends paid | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |
| FX effect on cash | 34.9M+329.3% | -15.2M-338.4% | 6.39M+186.0% | -7.43M+17.6% | -9.02M-283.4% | |
| Net change in cash | 690M+348.8% | 154M+386.5% | -53.7M-215.7% | 46.4M-85.6% | 323M+738.8% | |
| Interest paid | 219M+223.6% | 67.6M+110.4% | 32.1M-29.0% | 45.2M+83.5% | 24.7M | |
| Income taxes paid | 15.1M+5.1% | 14.4M+138.5% | 6.02M+126.9% | 2.65M | — | |
| Valuation Ratios | as ofDec 31 ’25 | as ofDec 31 ’24 | as ofDec 31 ’23 | as ofDec 31 ’22 | as ofDec 31 ’21 | |
| Market cap | 52.7B+73.1% | 30.5B+26.8% | 24.0B-17.8% | 29.2B+43.4% | 20.4B+34.1% | |
| P/E | 168.1× | — | — | — | — | |
| P/S | 14.2×+4.8% | 13.5×-2.8% | 13.9×-54.2% | 30.4×+26.0% | 24.1×-21.7% | |
| P/B | 66.8×-85.3% | 454.1× | — | — | 34.7×+131.6% | |
| P/FCF | 113.3× | — | — | — | — | |
| Earnings yield | 0.59% | — | — | — | — | |
| FCF yield | 0.88% | — | — | — | — | |
| Source filing | 10-K | 10-K | 10-K | 10-K | 10-K |
About this data
Source: ALNY’s SEC filings (10-K / 10-Q). Annual columns are as-reported fiscal years; quarterly columns are as-reported fiscal quarters (Q4 derived as full-year minus the first three quarters where a company doesn’t file a standalone Q4); TTM (quarterly) rolls the trailing four quarters at every quarter end, TTM (yearly) samples that one year apart; balance-sheet rows show the period-end balance. Valuation ratios are sampled as of each period end. View all ALNY filings on SEC EDGAR → Not investment advice.